EstraDerm is a physician-formulated transdermal cream featuring plant-based bioidentical estradiol and a minimal blend of supportive botanicals. Designed for efficient absorption through the skin, it delivers estrogen in a clean, toxin-free formula that works in synergy with your body’s natural hormonal rhythms. A gentle, plant-based approach to supporting estrogen levels during times of hormonal change.
“In one month I already notice a difference in my mood, sleep and skin, and love that it’s non-toxic and plant based!” — Emily F.
EstraDerm
EstraDerm
cruelty free
100% plant based
toxin free
EstraDerm is a physician-formulated transdermal cream featuring plant-based bioidentical estradiol and estriol. This minimalist formula is crafted with a gentle botanical blend and designed for efficient skin absorption, offering a clean, plant-based option to support estrogen levels and complement the body’s natural hormonal rhythms.
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Regular price
$42.00
Sale price
$27.99
1 FL. OZ./ 30 mL BOTTLE
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Restore Balance, Naturally.
Estrogen helps regulate essential functions like cognitive clarity, skin hydration, metabolic health, and emotional stability. When levels shift due to age, stress, or hormonal changes, that balance can be disrupted.
Bioidentical estrogen is derived from plant sources and has the same molecular structure as the estrogen your body naturally produces—which means it’s designed to work in harmony with your body’s existing hormonal pathways for more natural support.
When Estrogen Takes A Dive..
—We’ve got your parachute. Estrogen plays a central role in nearly every system of the body—from temperature regulation and brain function to skin elasticity, sleep quality, and emotional balance. It helps keep things running smoothly behind the scenes, which is why its slow decline can feel anything but subtle.
In perimenopause, menopause, or during periods of high stress, estrogen levels often drop—leaving your body to navigate shifting rhythms without one of its key regulators.
Backed by Science, Powered by Nature.
Balance
Bioidentical Estriol & Estradiol USP share the same molecular structure as your body’s natural estrogen and are used to support hormonal balance. Japanese Green Tea Extract contains compounds that may help modulate endocrine activity and promote a more stable hormonal environment.
Mood
Organic Aloe Vera and Vegetable Glycerin provide soothing hydration while supporting the skin’s stress barrier. Estriol & Estradiol USP have been studied for their role in influencing neurotransmitter activity related to emotional regulation.
Cognitive Health
Japanese Green Tea Extract offers antioxidant-rich polyphenols that help protect brain cells from oxidative stress. Estriol & Estradiol USP are linked to supporting cognitive function through their interaction with estrogen receptors in the brain.
Skin
Shea Butter and Organic Oils (Olive & Coconut) nourish and restore the skin’s moisture barrier. Estriol & Estradiol USP may help maintain skin elasticity, hydration, and collagen support—key elements in healthy, resilient skin.
Bioidentical Estriol & Estradiol (USP)
Plant-derived estrogens that share the same molecular structure as your body’s natural hormones
Japanese Green Tea Extract
A natural source of antioxidants and gentle caffeine to support energy and metabolic function.
Organic Aloe Vera & Vegetable Glycerin
Botanical hydrators that soothe skin, support cellular function, and aid ingredient absorption.
BiEST (80/20 Estriol & Estradiol USP)
Bioidentical estrogen blend for hormonal balance.
Grape Seed & Grapefruit Seed Extracts
Natural antimicrobial and antioxidant support.
Key Ingredients
Compassion is in our formula.
WE ARE LEAPING BUNNY APPROVED BY CRUELTY FREE INTERNATIONAL
While other brands rely on animal testing or use hormones sourced from animals, we do things differently here. Our Clean Hormones are proudly Leaping Bunny certified—100% cruelty-free, never tested on animals, and made with ethically sourced, plant-based ingredients. Because wellness should be in harmony with all living things, not built on their backs. We’re here for your health—and the health of the planet, too.
How to use EstraDerm ?
Every woman is different, so it is always recommended to start with a lower dose and work your way up to the recommended dosage, if needed.
Apply 1-3 pumps topically once or twice per day. If symptoms persist after 5 days, increase dose by 1-2 pumps. Wait 5 days, evaluate, and increase again if needed.
Our Clean Ethos
Formulated with bioidentical estrogen and organic botanicals, EstraDerm is designed with purity and quality in mind. Free from GMOs, parabens, soy, gluten, and synthetic fillers, it aligns with a clean and conscious approach to wellness.
Feel Good About Feeling Good.
At GLOW Natural Wellness, our formulas are 100% plant-based, cruelty and toxin free. We're CleanHub certified, plastic neutral, and recognized by the Clean Label Project for ingredient transparency. As we grow, we’re committed to expanding our efforts in sustainable sourcing and packaging—because true wellness means respecting the source—Mother Earth.
We are so confident that you will love the way EstraDerm makes you feel that we are offering a completely risk-free full 90-day money back guarantee.
FAQS
How can I get more support?
You can contact our customer service team via email or phone:
Email: support@glownaturalwellness.com
Phone: +1 (855) 928 4442
How do I know which hormones I need?
Can I see the full ingredient list?
Purified Water, Vegetable Glycerin, Organic Aloe Vera Leaf Gel, Estradiol USP*, Estriol USP*, Japanese Green Tea Extract*, Caprylic Capric Triglyceride, Stearic Acid, Organic Olive Oil, Organic Coconut Oil, Shea Butter, Sunflower Lecithin, Stearyl Alcohol, Vitamin E Acetate, Allantoin, Xanthan Gum, Grape Seed Extract*, Grapefruit Seed Extract*.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.