EstraDerm is a physician-formulated transdermal cream featuring plant-based bioidentical estradiol and a minimal blend of supportive botanicals. Designed for efficient absorption through the skin, it delivers estrogen in a clean, toxin-free formula that works in synergy with your body’s natural hormonal rhythms. A gentle, plant-based approach to supporting estrogen levels during times of hormonal change.
“In one month I already notice a difference in my mood, sleep and skin, and love that it’s non-toxic and plant based!” — Emily F.
EstraDerm
cruelty free
100% plant based
toxin free
EstraDerm is a physician-formulated transdermal cream featuring plant-based bioidentical estradiol and estriol. This minimalist formula is crafted with a gentle botanical blend and designed for efficient skin absorption, offering a clean, plant-based option to support estrogen levels and complement the body’s natural hormonal rhythms.
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$42.00
1 FL. OZ./ 30 mL BOTTLE
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Restore Balance, Naturally.
Estrogen helps regulate essential functions like cognitive clarity, skin hydration, metabolic health, and emotional stability. When levels shift due to age, stress, or hormonal changes, that balance can be disrupted.
Bioidentical estrogen is derived from plant sources and has the same molecular structure as the estrogen your body naturally produces—which means it’s designed to work in harmony with your body’s existing hormonal pathways for more natural support.
When Estrogen Takes A Dive..
—We’ve got your parachute. Estrogen plays a central role in nearly every system of the body—from temperature regulation and brain function to skin elasticity, sleep quality, and emotional balance. It helps keep things running smoothly behind the scenes, which is why its slow decline can feel anything but subtle.
In perimenopause, menopause, or during periods of high stress, estrogen levels often drop—leaving your body to navigate shifting rhythms without one of its key regulators.
Backed by Science, Powered by Nature.
Balance
Bioidentical Estriol & Estradiol USP share the same molecular structure as your body’s natural estrogen and are used to support hormonal balance. Japanese Green Tea Extract contains compounds that may help modulate endocrine activity and promote a more stable hormonal environment.
Mood
Organic Aloe Vera and Vegetable Glycerin provide soothing hydration while supporting the skin’s stress barrier. Estriol & Estradiol USP have been studied for their role in influencing neurotransmitter activity related to emotional regulation.
Cognitive Health
Japanese Green Tea Extract offers antioxidant-rich polyphenols that help protect brain cells from oxidative stress. Estriol & Estradiol USP are linked to supporting cognitive function through their interaction with estrogen receptors in the brain.
Skin
Shea Butter and Organic Oils (Olive & Coconut) nourish and restore the skin’s moisture barrier. Estriol & Estradiol USP may help maintain skin elasticity, hydration, and collagen support—key elements in healthy, resilient skin.
Bioidentical Estriol & Estradiol (USP)
Plant-derived estrogens that share the same molecular structure as your body’s natural hormones
Japanese Green Tea Extract
A natural source of antioxidants and gentle caffeine to support energy and metabolic function.
Organic Aloe Vera & Vegetable Glycerin
Botanical hydrators that soothe skin, support cellular function, and aid ingredient absorption.
Shea Butter & Organic Oils (Olive & Coconut)
Nourishes skin and supports absorption.
Grape Seed & Grapefruit Seed Extracts
Natural antimicrobial and antioxidant support.
Our Clean Ethos
At Glow Natural Wellness, our clean, simple formulas use bioidentical ingredients and are held to rigorous clean and ethical standards. Our plant-based products are cruelty-free and independently recognized by Leaping Bunny, the Clean Label Project for ingredient transparency, and CleanHub for plastic neutrality.
How to use EstraDerm
Every woman is different, so it is always recommended to start with a lower dose and work your way up to the recommended dosage, if needed.
Apply 1 or more pumps twice a day. If symptoms persist after 14 days, increase the number of pumps.
Need Help Personalizing Your Hormone Plan?
Our expert hormone coaches can help you choose the right products and build a plan that works for your body.
GET EXPERT SUPPORT HERE-
100% Vegan &
Gluten-Free -
Cruelty-Free
Certified -
Toxin-Free & Forever
Chemical-Free -
Climate Neutral
Partner -
Female Physician
Formulated -
3rd Party Tested
for Purity
FAQS
How can I get more support?
You can contact our customer service team via email or phone:
Email: support@glownaturalwellness.com
Phone: +1 (855) 928 4442
How do I know which hormones I need?
Can I see the full ingredient list?
Purified Water, Vegetable Glycerin, Organic Aloe Vera Leaf Gel, Estradiol USP*, Estriol USP*, Japanese Green Tea Extract*, Caprylic Capric Triglyceride, Stearic Acid, Organic Olive Oil, Organic Coconut Oil, Shea Butter, Sunflower Lecithin, Stearyl Alcohol, Vitamin E Acetate, Allantoin, Xanthan Gum, Grape Seed Extract*, Grapefruit Seed Extract*.
How much hormone is delivered per dose?
Each pump delivers approximately 0.25mg of bioidentical estradiol and 1mg of bioidentical estriol.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.